Cytoskeletal Signaling

Ipfencarbazone herbicide agent, is a substance being developed for the control of weeds such as …

Tubulin inhibitor 1 is an inhibitor of tubulin, inhibits tubulin polymerization, with potent anti-tumor activity, …

Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia …

PKC-theta inhibitor is PKC-θinhibitor, with an IC50 of 12 nM.

Debio 0932 is an orally active inhibitor of HSP90 (IC50s: 100 and 103 nM for …

Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through …

Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt …

Merestinib dihydrochloride is an effective and orally bioavailable c-Met inhibitor (Ki=2 nM). It has anti-tumor …

GW406108X (GW108X) is a Kif15 inhibitor with an IC50 of 0.82 uM in ATPase assays. …

YAP/TAZ inhibitor-1 is an inhibitor of YAP/TAZ (IC50 of <0.100 μΜ in firefly luciferase assay).

Epothilone D (KOS 862) is an effective microtubule stabilizer.

AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor (Ki: 43 nM; IC50: 300 nM …

Neoprzewaquinone A (NEO), an active ingredient of S. miltiorrhiza, inhibits breast cancer cell migration and …

(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.

Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of …

3-Deoxysappanchalcone is an effective HO-1 inducer at the translational level.

TD52 is an orally active inhibitor of cancerous inhibitor of PP2A (CIP2A). TD52 is an …

Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of …

ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 …

Maytansinol (Ansamitocin P-0) inhibits microtubule assembly and causes microtubule disassembly in vitro.