Beta amiloide

MK-0752, a γ-secretase inhibitor, reduces Aβ40 production(IC50=5 nM).

1. Schisantherin B (Schizantherin-B) shows good effect in lowering the serum glutamic-pyruvic transaminase level of …

ARN2966 is an inhibitor of amyloid precursor protein (APP)and amyloid-β (Aβ) secretion.

EUK-134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation …

Edonerpic maleate (T-817 maleate) is a neurotrophic agent which can inhibit amyloid-β peptides (Aβ).

LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. LX2343 acts …

Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β …

Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aα2(25-35)-induced neurotoxicity in PC12 cells, …

DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and …

LPYFD-NH2 acetate shows some inhibitory effect on the aggregation of Abeta(1-42).

Frentizole, an immunosuppressive agent, is an inhibitor of the Aβ-ABAD interaction

Scyllo-Inositol (Scyllitol) is one of the inositol stereoisomers, rare in the nature, and expected as …

Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.

TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. It inhibits cholinesterases AChE and …

TABERSONINE HYDROCHLORIDE is a natural product extracted from the bean of Voacanga africana, is a …

Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and …

Ginsenoside Rg2 (Chikusetsusaponin I) is one of the major active components of ginseng, act as …

MDR-1339 is a blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.

1. Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 …

Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.