kynureninase/KYNU Protein, Mouse, Recombinant (His)

Ref. TM-TMPY-02418

Información del producto

• Nombre: kynureninase/KYNU Protein, Mouse, Recombinant (His)
• Sinónimos: kynureninase, 4432411A05Rik

Descripción

KYNU (Kynureninase) is a Protein Coding gene. KYNU is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Genetic studies in the mouse and the human suggest that kynureninase activity may influence blood pressure and renal function. The gene coding kynureninase (KYNU) is also located on chromosome band 2q14-q23, where a linkage peak for essential hypertension was previously detected in the Chinese Han population. The results show that the rare KYNU variant Arg188Gln affects kynureninase activity and are consistent with the hypothesis that this mutation can predispose to essential hypertension. Diseases associated with KYNU include Hydroxykynureninuria and Vertebral, Cardiac, Renal, And Limb Defects Syndrome 2.

• Marca: Targetmol

Propiedades químicas

• Peso molecular: Approxiamtely 53.7 kDa
• Color/Forma: Solid