Neoechinulin A

CAS: 51551-29-2

Ref. TM-TN4635

Información del producto

• Nombre: Neoechinulin A
• CAS: 51551-29-2

Descripción

Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, it may block the phosphorylation of mitogen-activated protein kinase (MAPK) molecule p38, apoptosis signal-regulating kinase 1 (ASK-1) and nuclear translocation of nuclear factor-κB (NF-κB) p65 and p50 subunits, it has a potential to be developed as a modulator of neuroinflammatory process in Alzheimer's disease. Neoechinulin A may ameliorate rotenone toxicity by activating a cytoprotective machinery that requires ATP and antioxidant/anti-nitration activities.

• Marca: Targetmol

Propiedades químicas

• Peso molecular: 323.39
• Fórmula: C₁₉H₂₁N₃O₂
• Pureza: 98%
• Color/Forma: Solid