7-Bromo-2-chloroquinoline

CAS: 99455-15-9

Ref. 3D-FB33759

Product Information

• Name: 7-Bromo-2-chloroquinoline
• Synonyms: 7-Bromo-2-chloro quinoline, Quinoline, 7-bromo-2-chloro-
• CAS: 99455-15-9

Description

7-Bromo-2-chloroquinoline is an analog of quinoxaline. It is a potent antitumor agent that inhibits DNA synthesis and has been shown to be effective in treating solid cancers in both human and animal models. 7-Bromo-2-chloroquinoline binds to the putative target site on tumor cells, which is located on the surface of cancer cell lines, and inhibits the enzyme that catalyzes the conversion of phenylalanine to tyrosine. This enzyme is required for DNA synthesis and its inhibition leads to a decreased rate of cell division. The heterocyclic ring in this drug may react with DNA, resulting in cross linking and chain termination.

• Brand: Biosynth

Chemical properties

• Molecular weight: 242.5 g/mol
• Formula: C₉H₅BrClN
• Purity: Min. 95%
• InChI: InChI=1S/C9H5BrClN/c10-7-3-1-6-2-4-9(11)12-8(6)5-7/h1-5H
• InChI key: InChIKey=MOEWRAKNXMILKB-UHFFFAOYSA-N
• SMILES: Clc1ccc2ccc(Br)cc2n1