7-Deaza-2-mercaptoadenine

CAS: 98198-24-4

Ref. 3D-FD54469

Product Information

• Name: 7-Deaza-2-mercaptoadenine
• Synonyms: 4-Amino-7H-pyrrolo[2,3-?]pyrimidine-2-thiol, 4-Amino-1,7-dihydro-2H-pyrrolo[2,3-d]pyrimidine-2-thione, 4-amino-1,3-dihydro-2H-pyrrolo[2,3-d]pyrimidine-2-thione
• CAS: 98198-24-4

Description

7-Deaza-2-mercaptoadenine is a synthetic molecule that has been shown to be effective in vivo as an antibacterial agent against Gram-negative pathogens. It has been shown to have a comparable efficacy to the comparator, pleuromutilin. 7-Deaza-2-mercaptoadenine also showed activity against experimental infection with methicillin resistant Staphylococcus aureus (MRSA) and Clostridium difficile, which were not affected by comparator. 7-Deaza-2-mercaptoadenine is active against Gram negative bacteria by inhibiting protein synthesis through the inhibition of bacterial ribosomes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 166.2 g/mol
• Formula: C₆H₆N₄S
• Purity: Min. 95%
• InChI: InChI=1S/C6H6N4S/c7-4-3-1-2-8-5(3)10-6(11)9-4/h1-2H,(H4,7,8,9,10,11)
• InChI key: InChIKey=YZMVHADJFGBNBZ-UHFFFAOYSA-N
• SMILES: Nc1[nH]c(=S)nc2[nH]ccc12