(D-Pro4,D-Trp7·9·10)-Substance P (4-11)
CAS: 86917-57-9
Ref. 3D-FP109336
| 2mg | 176.00 € | ||
| 5mg | 316.00 € | ||
| 10mg | 459.00 € | ||
| 25mg | 873.00 € | ||
| 50mg | 1,429.00 € |
Product Information
- H-D-Pro-Gln-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH2 H-(dP)QQ(dW)F(dW)(dW)M-NH2
- (D-Pro4,D-Trp7910)-Substance P (4-11)
- H-D-Pro-Gln-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH2
Substance P is a neuropeptide that is found in the central nervous system. It is also found in the gastrointestinal tract and plays a role in the regulation of smooth muscle contraction. Substance P has been shown to be involved in inflammatory responses, immune responses, and regulation of water and electrolyte balance. The maximal response of substance P occurs at concentrations between 0.1 to 1 nM and its inhibitory effect on the apical Ca2+ response occurs at concentrations between 10-100 nM. In addition, substance P has been shown to have an excitatory effect on 5-HT7 receptors with subunit composition GluN1/GluN2A/GluN2B/GluN3A/5-HT7(H).
Chemical properties
Technical inquiry about: 3D-FP109336 (D-Pro4,D-Trp7·9·10)-Substance P (4-11)
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