6-Shogaol

CAS: 555-66-8

Ref. 3D-FS42771

Product Information

• Name: 6-Shogaol
• Synonyms: (4E)-1-(4-hydroxy-3-methoxyphenyl)dec-4-en-3-one, (E)-1-(4-Hydroxy-3-methoxy-phenyl)dec-4-en-3-one, 1-(4-Hydroxy-3-Methoxyphenyl)Dec-4-En-3-One, 1-(4-Hydroxy-3-methoxyphenyl)-4-decen-3-one, 4-Decen-3-one, 1-(4-hydroxy-3-methoxyphenyl)-, Shogaol
• CAS: 555-66-8

Description

A dehydration product of 6-gingerol and a major bioactive component of dried ginger with anti-inflammatory and anti-cancer properties. This compound induces apoptosis in cancer cells, impairs tubulin polymerization, downregulates NF-κB signalling, inhibits the expression of inflammatory mediators, and suppresses Toll-like receptor signalling. 6-Shogaol extracts have been shown to enhance antioxidant defence mechanisms by inducing Nrf2/ARE-mediated gene expression in cell and animal models. It can also activate transient receptor potential channels TRPV1 and TRPA1 (EC50 = 0.32 and 16 µM, respectively).

• Brand: Biosynth

Chemical properties

• Molecular weight: 276.37 g/mol
• Formula: C₁₇H₂₄O₃
• Purity: Min. 95%
• Color/Form: Clear Liquid
• InChI: InChI=1S/C17H24O3/c1-3-4-5-6-7-8-15(18)11-9-14-10-12-16(19)17(13-14)20-2/h7-8,10,12-13,19H,3-6,9,11H2,1-2H3/b8-7+
• InChI key: InChIKey=OQWKEEOHDMUXEO-BQYQJAHWSA-N
• SMILES: CCCCC/C=C/C(=O)CCc1ccc(O)c(OC)c1