5,6,7,40-Tetrahydroxyisoflavone-6,7-di-o-B-D-glucopyranoside
CAS: 1219001-04-3
Ref. 3D-UYB00104
| 1mg | To inquire | |
| 5mg | To inquire | |
| 10mg | To inquire | |
| 25mg | To inquire | |
| 50mg | To inquire |
Product Information
Cuspidata is an alkaloid that has been isolated from the plant Hypericum cuspidatum. It is a natural product with antibacterial and cytotoxic activities. Cuspidata inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Cuspidata also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.
Chemical properties
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