(-)-Variabilin
CAS: 370102-93-5
Ref. 3D-VPA10293
| 1mg | To inquire | |
| 5mg | To inquire | |
| 10mg | To inquire | |
| 25mg | To inquire | |
| 50mg | To inquire |
Product Information
(-)-Variabilin is a natural compound that has been shown to have anticancer activity. It is derived from the fatty acid, tetronic acid, and inhibits phosphatase activity. (-)-Variabilin binds to the catalytic site of protein tyrosine phosphatase 1B (PTP1B) and blocks its ability to dephosphorylate PTP-activated proteins, including insulin receptor substrate-1 (IRS-1). The structure of this active form is similar to deguelin, a synthetic compound that also inhibits PTP1B. The sequences of (-)-variabilin have been determined and it is possible that this molecule may be an analog of natural compounds found in plants such as mcf-7.
Chemical properties
Technical inquiry about: 3D-VPA10293 (-)-Variabilin
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