FGFR4-IN-14
Ref. TM-T79271
| 5mg | To inquire | |
| 50mg | To inquire |
Estimated delivery in United States, on Friday 17 May 2024
Product Information
Name:
FGFR4-IN-14
Description:
FGFR4-IN-14 (Compound 27i) is a selective FGFR4 inhibitor with an IC50 of 2.4 nM, showing potent inhibition of cell proliferation in the V550L and N535K mutant strains. Specifically, it registers IC50 values of 21 nM against Huh7 cells, 2.5 nM against BaF3/ETV6-FGFR4-V550L cells, and 171 nM against BaF3/ETV6-FGFR4-N535K cells. Demonstrating significant antitumor efficacy in the Huh7 xenograft model, FGFR4-IN-14 is utilized in the research of hepatocellular carcinoma (HCC) [1].
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
522.43
Formula:
C27H25Cl2N5O2
Purity:
98%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TM-T79271 FGFR4-IN-14
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