Prolyl Endopeptidase Protein, Mouse, Recombinant (His)
Ref. TM-TMPY-03269
| 50µg | 591.00 € |
Product Information
- PEP, AI450383, AI047692, D10Wsu136e, prolyl endopeptidase, Pop
Prolyl endopeptidase, also known as PREP, belongs to a distinct class of serine peptidases. It is a large cytosolic enzyme which was first described in the cytosol of rabbit brain as an oligopeptidase. Prolyl endopeptidase degrades the nonapeptide bradykinin at the Pro-Phe bond. It is involved in the maturation and degradation of peptide hormones and neuropeptides such as alpha-melanocyte-stimulating hormone, luteinizing hormone-releasing hormone (LH-RH), thyrotropin-releasing hormone, angiotensin, neurotensin, oxytocin, substance P and vasopressin. Prolyl endopeptidase's activity is confined to action on oligopeptides of less than 10 kD and it has an absolute requirement for the trans-configuration of the peptide bond preceding proline. It cleaves peptide bonds at the C-terminal side of proline residues.
Chemical properties
Technical inquiry about: TM-TMPY-03269 Prolyl Endopeptidase Protein, Mouse, Recombinant (His)
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