Amlexanox

CAS: 68302-57-8

Ref. TR-A633410

Product Information

• Name: Amlexanox
• Synonyms: 2-amino-5-oxo-7-propan-2-ylchromeno[2,3-b]pyridine-3-carboxylic acid, 2-Amino-5-oxo-7-propan-2-ylchromeno[2,3-b]pyridine-3-carboxylic acid, 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid, 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylicAcid, 2-Amino-7-isopropyl-1-azaxanthone-3-carboxylic Acid, 2-Amino-7-isopropyl-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic Acid, 2-Amino-7-isopropyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid, 2-Amino-7-isopropyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylicacid, 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid, 2-amino-7-(1-methylethyl)-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid, 5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid, 2-amino-7-(1-methylethyl)-5-oxo-, Aa 673, Amoxanox, Aphthasol, Aphtheal, Chx 3673, Elics, Solfa
• CAS: 68302-57-8

Description

Applications Inhibits release of allergic mediators from mast cells. Antiallergic; antiasthmatic. Amlexanox, used to treat asthma and mouth sores in humans, may also be a promising treatment for type 2 diabetes and obesity (Nat. Med., DOI: 10.1038/nm.3082).
References Rankov, G., et al.: Ophthalmic Res., 22, 359 (1990), Greer, R.O., et al.: J. Oral Mxillofac. Surg., 51, 243 (1993); Chem. and Eng. News p. 43, Feb. 18, 2013

• Brand: TRC

Chemical properties

• Molecular weight: 298.29
• Formula: C₁₆H₁₄N₂O₄
• Color/Form: Neat
• InChI: InChI=1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21)
• InChI key: InChIKey=SGRYPYWGNKJSDL-UHFFFAOYSA-N
• SMILES: CC(C)c1ccc2oc3nc(N)c(C(=O)O)cc3c(=O)c2c1