Receptor TAM

TAM-IN-2 is an inhibitor of TAM.

Tepotinib (EMD-1214063) is an inhibitor of MET tyrosine kinase with potential antineoplastic activity.

AXL-IN-13 is a potent and orally active AXL inhibitor with an IC50 value of 1.6 …

RU-302 is a pan inhibitor of TAM Receptor blocking the interface between the TAM Ig1 …

Axl-IN-16, a dual Axl/HIF inhibitor, promotes Flammulina velutipes fruiting body formation and suppresses hypoxia-inducible factor …

Enapotamab is an AXL/UFO-related antibody that can be used to synthesize antibody-drug couplings (Enapotamab Vedotin).

Gilteritinib hemifumarate (ASP2215 hemifumarate) is a potent ATP-competitive dual FLT3 (IC50: 0.29 nM) and AXL …

UNC 569 hydrochloride is a reversible and ATP-competitive inhibitor of Mer with an IC50 of …

AXL-IN-15 (cpd391) is a potent inhibitor of Axl, exhibiting both a dissociation constant (K i) …

Emactuzumab(RG 7155) is a monoclonal antibody against colony-stimulating factor-1 receptor targeting tumor-associated macrophages (TAMs) Emactuzumab …

UNC569 (UNC 569) is a selective inhibitor of URAT1, a transporter in the kidney that …

BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met/Axl/Ron/Tyro3 (IC50: 3.9/1.1/1.8/4.3 nM). BMS-777607 has …

UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM …

CEP-40783 (RXDX-106) is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It …

Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and …

G-749, a new-type FLT3 inhibitor, exhibits effective and sustained inhibition of the FLT3 wild type …

Cabozantinib S-malate (XL184) is the s-malate salt form of cabozantinib, an orally bioavailable, small molecule …

S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3, blocking cellular phosphorylation of …

DS-1205 is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 …

Dubermatinib (TP0903) is a potent and selective Axl kinase inhibitor.