c-RET

trans-Pralsetinib (trans-BLU-667) is an inhibitor of rearranged during transfection (RET).

Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for …

Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, …

BT-13 is a selective agonist of glial cell line-derived neurotrophic factor (GDNF) receptor RET independently …

RET-IN-3 is a RETV804M kinase inhibitor with potential anticancer activity for the study of non-small …

Compound TPX-0046 is an inhibitor of RET. Compound TPX-0046 can inhibit the RET autophosphorylation. Compound …

Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks …

Agerafenib hydrochloride is a highly potent inhibitor of BRAFV600E (Kd: 14 nM).

TG-89 is an inhibitor of JAK2, JAK3, RET and FLT3, and has an IC50 value …

DUN73423 (RET-IN-21) is a potent tyrosine kinase (RET) inhibitor with antitumour activity for the study …

Enbezotinib is an inhibitor of RET autophosphorylation and can be used in cancer research.

Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less …

WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and …

AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.

Treprostinil Sodium (UT-15) is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM).

ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).

Ilorasertib (ABT-348) (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C …

SPP-86 is an effective and selective cell-permeable inhibitor of RET tyrosine kinase with an IC50 …

Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, …

RPI-1 is a competitive, potent ATP-dependent Ret kinase inhibitor.