Ras
In this category you can find inhibitors of Ras proteins. Ras proteins are part of the targeting process of mitogen-activated protein kinase pathways, which is a signalling pathway in eukaryotic cells.
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KRAS G12C inhibitor 60
KRAS G12C Inhibitor 60 (compound 23), a selective inhibitor targeting the Kras-G12C mutation, is utilized …
Formula:
C31H30F5N7O2
Purity:
98%
Molecular weight:
627.61
Ref: TM-T79166
5mg | To inquire | |
50mg | To inquire |
Estimated delivery in United States, on Monday 3 Jun 2024
KRAS G12C inhibitor 59
CAS:2914919-88-1
KRAS G12C Inhibitor 59 is a compound with anticancer properties.
Formula:
C32H39F6N7O5
Purity:
98%
Molecular weight:
715.69
Ref: TM-T79150
5mg | To inquire | |
50mg | To inquire |
Estimated delivery in United States, on Monday 3 Jun 2024
RMC-7977
CAS:2765082-12-8
RMC-7977 is a highly selective inhibitor of the active (GTP-bound) forms of KRAS, HRAS, and …
Formula:
C47H60N8O6S
Purity:
97.46%
Color and Shape:
Solid
Molecular weight:
865.09
Ref: TM-T81263
1mg | 758.00 € | |
5mg | 1,853.00 € | |
10mg | 2,779.00 € | |
25mg | 4,323.00 € |
Estimated delivery in United States, on Monday 3 Jun 2024
GGTI298 Trifluoroacetate
CAS:1217457-86-7
GGTI298 Trifluoroacetate (GGTI 298 TFA salt) is a geranylgeranyltransferase I inhibitor with ability to arrest …
Formula:
C27H33N3O3S·C2HF3O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
593.66
Ref: TM-T6844
1mg | To inquire | |
5mg | To inquire | |
10mg | To inquire | |
25mg | To inquire | |
50mg | To inquire | |
1ml*10 (DMSO) | To inquire |
Estimated delivery in United States, on Monday 3 Jun 2024
Divarasib
CAS:2417987-45-0
Divarasib (GDC-6036) (GDC-6036) is an investigational, oral, high-potency and selective KRAS G12C inhibitor with an …
Formula:
C29H32ClF4N7O2
Purity:
98.79%
Color and Shape:
Solid
Molecular weight:
622.06
Ref: TM-T9972
1mg | 228.00 € | |
5mg | 571.00 € | |
10mg | 810.00 € | |
25mg | 1,233.00 € | |
50mg | 1,653.00 € | |
100mg | 2,209.00 € |
Estimated delivery in United States, on Monday 3 Jun 2024
CCG-222740
CAS:1922098-69-8
CCG-222740 is an inhibitor of Rho/MRTF pathway
Formula:
C23H19ClF2N2O3
Purity:
98.79%
Color and Shape:
Solid
Molecular weight:
444.86
Ref: TM-T7764
1mg | 48.00 € | |
2mg | 64.00 € | |
5mg | 95.00 € | |
10mg | 163.00 € | |
25mg | 298.00 € | |
50mg | 455.00 € | |
100mg | 674.00 € | |
1ml*10 (DMSO) | 104.00 € |
Estimated delivery in United States, on Tuesday 11 Jun 2024
Salirasib
CAS:162520-00-5
Salirasib (Farnesyl Thiosalicylic Acid)(Ki=2.6 μM), an effective competitive prenylated protein methyltransferase (PPMTase) inhibitor, inhibits Ras …
Formula:
C22H30O2S
Purity:
99.33%
Color and Shape:
Solid
Molecular weight:
358.54
Ref: TM-T6163
5mg | 35.00 € | |
10mg | 52.00 € | |
25mg | 94.00 € | |
50mg | 157.00 € | |
100mg | 217.00 € | |
200mg | 356.00 € | |
500mg | 587.00 € | |
1ml*10 (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 11 Jun 2024
Kobe2602
CAS:454453-49-7
Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities.
Formula:
C14H9F4N5O4S
Purity:
99.39%
Color and Shape:
Solid
Molecular weight:
419.31
Ref: TM-T1892
10mg | 40.00 € | |
25mg | 52.00 € | |
50mg | 80.00 € | |
100mg | 121.00 € | |
1ml*10 (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 11 Jun 2024
Arglabin
CAS:84692-91-1
Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, …
Formula:
C15H18O3
Purity:
99.62%
Color and Shape:
Solid
Molecular weight:
246.3
Ref: TM-TQ0165
1mg | 103.00 € | |
5mg | 235.00 € | |
10mg | 352.00 € | |
25mg | 510.00 € | |
50mg | 678.00 € | |
100mg | 1,013.00 € | |
1ml*10 (DMSO) | 304.00 € |
Estimated delivery in United States, on Tuesday 11 Jun 2024
BQU57
CAS:1637739-82-2
BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor …
Formula:
C16H13F3N4O
Purity:
98.72%
Color and Shape:
Solid
Molecular weight:
334.3
Ref: TM-T2267
2mg | 45.00 € | |
5mg | 60.00 € | |
10mg | 90.00 € | |
25mg | 159.00 € | |
50mg | 184.00 € | |
100mg | 345.00 € | |
1ml*10 (DMSO) | 67.00 € |
Estimated delivery in United States, on Tuesday 11 Jun 2024
Sotorasib
CAS:2296729-00-3
Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C. Sotorasib binds …
Formula:
C30H30F2N6O3
Purity:
99.88%
Color and Shape:
Solid
Molecular weight:
560.59
Ref: TM-T8684
1g | 1,338.00 € | |
1mg | 37.00 € | |
2mg | 52.00 € | |
5mg | 78.00 € | |
10mg | 124.00 € | |
25mg | 222.00 € | |
50mg | 368.00 € | |
100mg | 452.00 € | |
500mg | 1,010.00 € | |
1ml*10 (DMSO) | 97.00 € |
Estimated delivery in United States, on Tuesday 11 Jun 2024
KRAS inhibitor-9
CAS:300809-71-6
KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks …
Formula:
C13H9ClN2S2
Purity:
99.94%
Color and Shape:
Solid
Molecular weight:
292.81
Ref: TM-T8756
1mg | 60.00 € | |
2mg | 84.00 € | |
5mg | 118.00 € | |
10mg | 185.00 € | |
25mg | 346.00 € | |
50mg | 500.00 € | |
100mg | 641.00 € | |
1ml*10 (DMSO) | 141.00 € |
Estimated delivery in United States, on Tuesday 11 Jun 2024
ML-099
CAS:496775-95-2
ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A …
Formula:
C14H13NO2S
Purity:
99.48%
Color and Shape:
Solid
Molecular weight:
259.32
Ref: TM-T22991
1mg | 48.00 € | |
2mg | 63.00 € | |
5mg | 94.00 € | |
10mg | 149.00 € | |
25mg | 300.00 € | |
50mg | 476.00 € | |
100mg | 694.00 € | |
1ml*10 (DMSO) | 92.00 € |
Estimated delivery in United States, on Tuesday 11 Jun 2024
CID44216842
CAS:1222513-26-9
CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 …
Formula:
C22H20BrN3O3S
Purity:
99.63%
Color and Shape:
Solid
Molecular weight:
486.38
Ref: TM-T8930
1mg | 40.00 € | |
2mg | 52.00 € | |
5mg | 86.00 € | |
10mg | 132.00 € | |
25mg | 263.00 € | |
50mg | 420.00 € | |
100mg | 620.00 € | |
1ml*10 (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 11 Jun 2024
MLS000532223
CAS:16616-39-0
MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).
Formula:
C15H9NO3
Purity:
98.11%
Color and Shape:
Solid
Molecular weight:
251.24
Ref: TM-T8473
1mg | 127.00 € | |
2mg | 180.00 € | |
5mg | 300.00 € | |
10mg | 454.00 € | |
25mg | 743.00 € | |
50mg | 1,019.00 € | |
100mg | 1,389.00 € | |
1ml*10 (DMSO) | 311.00 € |
Estimated delivery in United States, on Tuesday 11 Jun 2024
APS6-45
CAS:2188236-41-9
APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.
Formula:
C23H16F8N4O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
548.39
Ref: TM-T8843
1mg | 80.00 € | |
5mg | 171.00 € | |
10mg | 269.00 € | |
25mg | 492.00 € | |
50mg | 714.00 € | |
100mg | 1,003.00 € | |
1ml*10 (DMSO) | 203.00 € |
Estimated delivery in United States, on Tuesday 11 Jun 2024
CCG-100602
CAS:1207113-88-9
CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).
Formula:
C21H17ClF6N2O2
Purity:
99.86%
Color and Shape:
Solid
Molecular weight:
478.82
Ref: TM-T22062
5mg | 38.00 € | |
10mg | 56.00 € | |
25mg | 113.00 € | |
50mg | 185.00 € | |
100mg | 298.00 € | |
200mg | 442.00 € | |
1ml*10 (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 11 Jun 2024
K-Ras(G12C) Inhibitor 6
CAS:2060530-16-5
K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% …
Formula:
C17H22Cl2N2O3S
Purity:
100%
Color and Shape:
Solid
Molecular weight:
405.33
Ref: TM-T3725
1mg | 62.00 € | |
2mg | 87.00 € | |
5mg | 130.00 € | |
10mg | 226.00 € | |
25mg | 470.00 € | |
50mg | 656.00 € | |
100mg | 915.00 € | |
1ml*10 (DMSO) | 131.00 € |
Estimated delivery in United States, on Tuesday 11 Jun 2024
Rhosin hydrochloride
CAS:1281870-42-5
Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds …
Formula:
C20H20Cl2N6O
Purity:
98.92%
Color and Shape:
Solid
Molecular weight:
431.318
Ref: TM-T16745
1mg | 157.00 € | |
2mg | 213.00 € | |
5mg | 322.00 € | |
10mg | 462.00 € | |
25mg | 741.00 € | |
50mg | 1,007.00 € | |
100mg | 1,347.00 € | |
1ml*10 (DMSO) | 357.00 € |
Estimated delivery in United States, on Tuesday 11 Jun 2024
ML-210
CAS:1360705-96-9
ML-210 (CID 49766530) is a selective RAS and covalent glutathione peroxidase 4 (GPX4) inhibitor(GPX4, EC50 …
Formula:
C22H20Cl2N4O4
Purity:
97%
Color and Shape:
Solid
Molecular weight:
475.32
Ref: TM-T8375
1mg | 40.00 € | |
2mg | 52.00 € | |
5mg | 85.00 € | |
10mg | 138.00 € | |
25mg | 242.00 € | |
50mg | 406.00 € | |
100mg | 584.00 € | |
200mg | 828.00 € | |
500mg | 1,226.00 € | |
1ml*10 (DMSO) | 90.00 € |
Estimated delivery in United States, on Tuesday 11 Jun 2024