Ras
In this category you can find inhibitors of Ras proteins. Ras proteins are part of the targeting process of mitogen-activated protein kinase pathways, which is a signalling pathway in eukaryotic cells.
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BI-3406
CAS:2230836-55-0
BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless …
Formula:
C23H25F3N4O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
462.46
Ref: TM-T12979
1mg | 72.00 € | |
5mg | 157.00 € | |
10mg | 245.00 € | |
25mg | 453.00 € | |
50mg | 649.00 € | |
100mg | 903.00 € | |
500mg | 1,793.00 € | |
1ml*10 (DMSO) | 172.00 € |
Estimated delivery in United States, on Wednesday 22 May 2024
K-Ras G12C-IN-4
CAS:2376328-55-9
K-Ras G12C-IN-4 is a potent co-valent Inhibitor of KRAS G12C..
Formula:
C31H33ClN4O4
Purity:
99.00%
Color and Shape:
Solid
Molecular weight:
561.07
Ref: TM-T11738
1mg | 143.00 € | |
2mg | 204.00 € | |
5mg | 347.00 € | |
10mg | 518.00 € | |
25mg | 835.00 € | |
50mg | 1,137.00 € | |
100mg | 1,537.00 € | |
1ml*10 (DMSO) | 428.00 € |
Estimated delivery in United States, on Wednesday 22 May 2024
ARS-1630
CAS:1698055-86-5
ARS-1630 is a mutant K-ras G12C inhibitor. It is a less active enantiomer of ARS-1620.
Formula:
C21H17ClF2N4O2
Purity:
97.81%
Color and Shape:
Solid
Molecular weight:
430.84
Ref: TM-T10376
1mg | 91.00 € | |
5mg | 185.00 € | |
10mg | 270.00 € | |
25mg | 534.00 € | |
50mg | 766.00 € | |
100mg | 1,006.00 € | |
1ml*10 (DMSO) | 211.00 € |
Estimated delivery in United States, on Wednesday 22 May 2024
HJC0197
CAS:1383539-73-8
HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 is an effective exchange protein. Which straightly activated …
Formula:
C19H21N3OS
Purity:
99.76%
Color and Shape:
Solid
Molecular weight:
339.45
Ref: TM-T15485
1mg | 45.00 € | |
5mg | 91.00 € | |
10mg | 126.00 € | |
25mg | 212.00 € | |
50mg | 345.00 € | |
100mg | 510.00 € | |
1ml*10 (DMSO) | 94.00 € |
Estimated delivery in United States, on Wednesday 22 May 2024
MBQ-167
CAS:2097938-73-1
MBQ-167 is a dual inhibitor of Rac/Cdc42 (IC50s: 103 nM for Rac 1/2/3 and 78 …
Formula:
C22H18N4
Purity:
98.07%
Color and Shape:
Solid
Molecular weight:
338.41
Ref: TM-T16021
1mg | 36.00 € | |
2mg | 52.00 € | |
5mg | 78.00 € | |
10mg | 109.00 € | |
25mg | 204.00 € | |
50mg | 370.00 € | |
100mg | 553.00 € | |
1ml*10 (DMSO) | 85.00 € |
Estimated delivery in United States, on Wednesday 22 May 2024
MRTX-1257
CAS:2206736-04-9
MRTX-1257 is a selective, irreversible, and covalent inhibitor of KRAS G12C. It has an IC50 …
Formula:
C33H39N7O2
Purity:
99.07%
Color and Shape:
Solid
Molecular weight:
565.71
Ref: TM-T16143
1mg | 63.00 € | |
2mg | 89.00 € | |
5mg | 128.00 € | |
10mg | 215.00 € | |
25mg | 364.00 € | |
50mg | 547.00 € | |
100mg | 783.00 € | |
1ml*10 (DMSO) | 172.00 € |
Estimated delivery in United States, on Wednesday 22 May 2024
Ketoconazole
CAS:65277-42-1
Ketoconazole (R-41400), a CYP3A4 inhibitor, is an imidazole anti-fungal agent.
Formula:
C26H28Cl2N4O4
Purity:
99.62%
Color and Shape:
Crystals From 4-Methylpentanone Solid
Molecular weight:
531.43
Ref: TM-T0679
1g | 99.00 € | |
5g | 343.00 € | |
50mg | 44.00 € | |
100mg | 55.00 € | |
200mg | 67.00 € | |
500mg | 83.00 € | |
1ml*10 (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 22 May 2024
PROTAC KRAS G12C degrader-3
CAS:2768099-51-8
PROTAC KRAS G12C Degrader-3 (Comp 283) serves as a potent degrader of KRAS G12C, utilized …
Formula:
C63H75ClN14O6
Purity:
98%
Molecular weight:
1159.81
Ref: TM-T79148
5mg | To inquire | |
50mg | To inquire |
Estimated delivery in United States, on Thursday 23 May 2024
Garsorasib
CAS:2559761-14-5
Garsorasib is an effective KRAS G12C inhibitor (IC50 = 10 nM) and can be used …
Formula:
C32H32F2N8O2
Purity:
98.99%
Color and Shape:
Solid
Molecular weight:
598.65
Ref: TM-T40186
1mg | 148.00 € | |
2mg | 212.00 € | |
5mg | 361.00 € | |
10mg | 550.00 € | |
25mg | 881.00 € | |
50mg | 1,189.00 € | |
100mg | 1,607.00 € | |
1ml*10 (DMSO) | 460.00 € |
Estimated delivery in United States, on Thursday 23 May 2024
TH-Z827
CAS:2847881-81-4
TH-Z827 is a mutant-selective inhibitor targeting KRAS(G12D) with an IC50 of 2.4 μM, demonstrating specificity …
Formula:
C30H38N6O
Purity:
98%
Molecular weight:
498.66
Ref: TM-T79092
5mg | To inquire | |
50mg | To inquire |
Estimated delivery in United States, on Thursday 23 May 2024
LUNA18
CAS:2676177-63-0
LUNA18 is an orally active inhibitor targeting KRAS, exhibiting potent activity with an IC50 value …
Formula:
C73H105F5N12O12
Purity:
98%
Molecular weight:
1437.68
Ref: TM-T79673
5mg | To inquire | |
50mg | To inquire |
Estimated delivery in United States, on Thursday 23 May 2024
ESI-08
CAS:301177-43-5
ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively …
Formula:
C20H23N3OS
Purity:
99.05%
Color and Shape:
Solid
Molecular weight:
353.48
Ref: TM-T11234
1mg | 55.00 € | |
5mg | 118.00 € | |
10mg | 185.00 € | |
25mg | 425.00 € | |
50mg | 624.00 € | |
1ml*10 (DMSO) | 162.00 € |
Estimated delivery in United States, on Thursday 23 May 2024
pan-KRAS-IN-2
CAS:2882825-14-9
Pan-KRAS-IN-2 (compound 6) is a broad-spectrum KRAS inhibitor exhibiting potent activity with IC50 values of …
Formula:
C34H34F2N4O3
Purity:
98%
Molecular weight:
584.66
Ref: TM-T79800
5mg | To inquire | |
50mg | To inquire |
Estimated delivery in United States, on Thursday 23 May 2024
(R)-BI-2852
CAS:2375482-49-6
(R)-BI-2852 can be used as (R)-5-isoindolin-1-one is used as an inhibitor of the RAS family …
Formula:
C31H28N6O2
Purity:
97.78%
Color and Shape:
Soild
Molecular weight:
516.59
Ref: TM-T72084
1mg | 138.00 € | |
5mg | 255.00 € | |
10mg | 399.00 € | |
25mg | 646.00 € | |
50mg | 898.00 € | |
100mg | 1,198.00 € |
Estimated delivery in United States, on Thursday 23 May 2024
AZD4747
CAS:2489226-14-2
AZD4747 is a selective and potent inhibitor of the mutant GTPase KRASG12C that crosses the …
Formula:
C24H22ClFN2O3
Purity:
99.36%
Color and Shape:
Solid
Molecular weight:
440.89
Ref: TM-T79213
1mg | 248.00 € | |
5mg | 606.00 € | |
10mg | 918.00 € | |
25mg | 2,026.00 € | |
50mg | 3,243.00 € | |
100mg | 5,222.00 € |
Estimated delivery in United States, on Thursday 23 May 2024
Sevelamer Carbonate
CAS:845273-93-0
Sevelamer carbonate is a non-absorbed phosphate binding crosslinked polymer, with the same polymeric structure as …
Formula:
(C3H7N·C3H5ClO)x·xCH2O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
211.64
Ref: TM-T6666
25mg | To inquire | |
100mg | To inquire | |
200mg | To inquire |
Estimated delivery in United States, on Thursday 23 May 2024
KRAS G12D modulator-1
CAS:2883034-05-5
KRAS G12D modulator-1 (compound 6), a potent modulator of KRAS G12D, exhibits IC50 values ranging …
Formula:
C30H36FN5O4
Purity:
98%
Molecular weight:
549.64
Ref: TM-T79072
5mg | To inquire | |
50mg | To inquire |
Estimated delivery in United States, on Thursday 23 May 2024
MC 976
CAS:129831-99-8
MC 976 is a derivative of Vitamin D3.
Formula:
C27H42O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
414.63
Ref: TM-T16023
1mg | To inquire |
Estimated delivery in United States, on Thursday 23 May 2024
Opnurasib
CAS:2653994-08-0
Opnurasib (JDQ-443) is an orally available and selective and potent covalent KRAS G12C inhibitor with …
Formula:
C29H28ClN7O
Purity:
98.88%
Color and Shape:
Solid
Molecular weight:
526.03
Ref: TM-T40292
1mg | 103.00 € | |
5mg | 348.00 € | |
10mg | 517.00 € | |
25mg | 835.00 € | |
50mg | To inquire | |
1ml*10 (DMSO) | 400.00 € |
Estimated delivery in United States, on Thursday 23 May 2024
PROTAC K-Ras Degrader-1
CAS:2378258-52-5
PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC.
Formula:
C53H62N10O10
Purity:
98%
Color and Shape:
Solid
Molecular weight:
999.12
Ref: TM-T13844
1mg | To inquire | |
5mg | To inquire | |
10mg | To inquire | |
50mg | To inquire | |
100mg | To inquire |
Estimated delivery in United States, on Thursday 23 May 2024